Prof. Hagit Eldar-Finkelman
Medicine
Research work
Our research is focused on uncovering cellular mechanisms leading to disease pathogenesis with a particular emphasis on drug development. We aim to develop strategic platform for rational discovery and design of protein kinase inhibitors using computational and biochemical tools.
Our current work focus on the role of degradation pathways such as autophagy in controlling neurotoxic protein aggregation and the ways to intensify cellular clearance, using models of Alzheimer's and Huntington's disease.
Research Affiliation
Medicine
- School of Medicine
Open Research Positions
PhD
Publication date:
April 9 2024
Position Type:
PhD
About the position:
Research Projects:
- Research in the area of cellular signaling, protein biochemistry and drug development in the neurosciences arena.
- Study the mechanisms underlying aggregation of neurotoxic protein, degradation pathways, mitochondria damage and oxidative stress
- Use multiple methodologies for drug screening including computational tools
- Work with tissue cultured cells, primary neurons, conduct biochemical analysis including western blots, enzymology assays, FACS, and con-focal microscopy.
Candidacy Requirements:
