Prof. Moran Rubinstein
Medicine, Neuroscience
Research work
We investigate the neuronal and molecular mechanisms underlying severe epilepsy and autism, with a particular focus on genetic developmental epilepsy syndromes. Our current research centers on Dravet syndrome, GRIN2D-related epileptic encephalopathy, and CHD2-related epileptic encephalopathy.
Our studies aim to:
- Uncover the neuronal and molecular mechanisms driving these disorders.
- Develop innovative viral-mediated genetic therapies to alleviate both epileptic and non-epileptic symptoms.
- Identify clinically relevant biomarkers to assess the therapeutic effects of current and emerging treatments.
- This research provides critical insights into disease pathology while paving the way for novel therapeutic strategies.
Human research includes pupillometry and gaze estimation, memory performance tests and machine learning methodology.
Research Affiliation
Medicine
- School of Medicine
Neuroscience
Open Research Positions
PhD Candidate
Publication date:
March 12 2025
Position Type:
PhD
About the position:
Working with mouse models, we conduct intraparenchymal viral injections, in vivo and ex vivo electrophysiological experiments, chemogenetic manipulations, and behavioral paradigms to investigate neuronal mechanism and the effect of therapeutic interventions.
Candidacy Requirements:
